PD-L1 binding fibronectin type III domains

US10597438B2 · kind B2 · utility

Assignee

• JANSSEN BIOTECH, INC. · US

Inventors

• Michael Diem · Havertown, US
• Rebecca Hawkins · Harleysville, US
• Steven Jacobs · North Wales, US
• Manuel Sepulveda · Princeton Junction, US

Key dates

• Filing date: Dec 13, 2017
• Grant date: Mar 24, 2020
• Expiry date: Dec 13, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/61
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

FN3 domains that specifically bind to PD-L1, their conjugates, isolated nucleotides encoding the molecules, vectors, host cells, and methods of making and using them are useful in therapeutic and diagnostic applications.