Molecule detection using boronic acid substituted probes
US10597702B2 · kind B2 · utility
1Cited by
0References
15Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 26, 2014 |
| Grant date | Mar 24, 2020 |
| Priority date | — |
| Expiry date | Jul 30, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/533
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided are polymeric scaffold compositions and methods for detecting or quantitating diols such as carbohydrates or carbohydrate containing molecules (e.g., glycosylated protein). Provided herein are capture probes configured to bind to a scaffold. Also provided herein are capture probes linked to one or more reactive organoboronic moiety for binding diol-containing compounds in a solution. Methods of detecting complexes comprising diol-containing compounds for detecting or quantifying the presence of diol-containing compounds in solution using a nanopore device are also provided herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.