Methods and systems for the detection of analytes
US10598625B2 · kind B2 · utility
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24Claims
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Key dates
| Filing date | Apr 8, 2016 |
| Grant date | Mar 24, 2020 |
| Priority date | — |
| Expiry date | Mar 16, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/58
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided herein are methods and devices for the detection of analytes. The methods employ particles formed from a first metal conjugated to analytes. The analyte conjugated to the particle formed from the first metal can be accumulated at a working electrode. The first metal can be galvanically exchanged with ions of a second metal to form a layer of the first metal at the working electrode. The first metal can then be electrochemically detected and/or quantified. Using this method, analytes can be detected at low concentrations a few femtomolar via anodic stripping voltammetry, with no washing steps or electrode modifications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.