Methods of blocking cancer stem cell growth

US10598653B2 · kind B2 · utility

Assignee

• Bionomics Limited · AU

Inventors

• Christopher L. Reyes · Adelaide, AU
• Peter Chu · Hawthorne, US
• Xiangyang Tan · Tewksbury, US
• Weixing Yang · Newton, US
• Christilyn Graff · Cambridge, US

Key dates

• Filing date: Oct 31, 2012
• Grant date: Mar 24, 2020
• Expiry date: Nov 28, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are antibodies against GPR49 and uses of such antibodies. The antibodies can be monoclonal, humanized, or fully human antibodies against GPR49, hybridomas or other cell lines expressing such antibodies, nucleic acids and vectors comprising nucleic acids encoding for such antibodies, and methods of blocking cancer stem cell growth with such antibodies.