Active ingredient containing stabilised solid medicinal forms and methods for the production thereof

US10603280B2 · kind B2 · utility

Assignee

• Losan Pharma GmbH · DE

Inventors

• Peter Gruber · Bottmingen, CH
• Dirk Spickermann · Staufen, DE

Key dates

• Filing date: Dec 7, 2018
• Grant date: Mar 31, 2020
• Expiry date: Dec 7, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.