Patent · US Active

Small molecules targeting HIV-1 nef

US10603321B2 · kind B2 · utility

0Cited by

4References

11Claims

0Family size

Assignee

University of Pittsburgh—Of the Commonwealth System of Higher Education · US

Inventor

Thomas E. Smithgall · Wexford, US

Key dates

Filing date	Feb 15, 2018
Grant date	Mar 31, 2020
Priority date	—
Expiry date	Feb 15, 2038

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K45/06
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A method of treating HIV in a subject, comprising administering to a subject in need thereof a therapeutically effective amount of a compound having a general Formula 1, or a pharmaceutically acceptable salt or ester thereof: wherein R1 is selected from H, optionally-substituted aryl, optionally-substituted heteroaryl, or optionally-substituted aliphatic; each R2 is independently selected from H, halogen, cyano, thioether, oxo, optionally-substituted amino, optionally-substituted heteroaryl, optionally-substituted aryl, or optionally-substituted aliphatic; a is 3 to 7; and the ring designates a heterocyclic or heteroaryl structure.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.