(Thio, oxo, and seleno) semicarbazone derivatives and their use for treating cancer

US10604480B2 · kind B2 · utility

Assignees

• Rutgers, the State University of New Jersey · US
• The Research Foundation for The State University of New York · US

Inventors

• David J. Augeri · Princeton, US
• Anthony F. Bencivenga · New Brunswick, US
• Adam Blanden · Manlius, US
• Darren R. Carpizo · New Brunswick, US
• John A. Gilleran · New Brunswick, US
• Spencer David Kimball · Plainsboro, US
• Stewart N. Loh · Manlius, US
• Xin Yu · South San Francisco, US

Key dates

• Filing date: Jan 27, 2016
• Grant date: Mar 31, 2020
• Expiry date: Jan 27, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D403/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides compounds of formula I and II and salts thereof, wherein R1, R2, Y, R3, and R4 have any of the meanings described in the specification, as well as compositions comprising such compounds and salts, and methods for treating cancer using such compounds and salts.