CFTR regulators and methods of use thereof

US10604492B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Alan S. Verkman · San Francisco, US
• Marc H. Levin · San Francisco, US
• Onur Cil · Oakland, US
• Sujin Lee · Yongin-si, KR

Key dates

• Filing date: Dec 23, 2016
• Grant date: Mar 31, 2020
• Expiry date: Dec 23, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided herein are compounds that activate CFTR and methods for treating constipation, dry eye disorders, and other diseases and disorders.