Engineered enzyme for enzyme replacement therapy
US10604747B2 · kind B2 · utility
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Key dates
| Filing date | Aug 5, 2016 |
| Grant date | Mar 31, 2020 |
| Priority date | — |
| Expiry date | Sep 11, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An engineered enzyme, comprising an amino acid sequence that is at least 80% identical to the amino acid sequence of a human beta-glucuronidase, wherein the engineered enzyme exhibits a higher level of alpha-iduronidase enzymatic activity as compared to the human beta-glucuronidase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.