Systems and methods for detecting metal ion concentrations in subjects
US10605799B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 11, 2017 |
| Grant date | Mar 31, 2020 |
| Priority date | — |
| Expiry date | Aug 6, 2037 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D2257/60
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of selective detection of a concentration of a metal ion species in a subject is provided in which a biofluid sample is obtained from the subject. The biofluid sample is exposed to a functionalized porous aromatic polymer. The polymer selectively captures and concentrates the metal ion species from the biofluid. Subsequently, the biofluid is washed from the polymer. The polymer is then exposed to a solution comprising a colorimetric indicator that extracts the metal ion species from the washed polymer thereby changing a color of the solution as a function of an amount of the metal ion species in the polymer. The concentration of the metal ion species in the subject is then spectroscopically determined from the color of the solution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.