Patent · US Active

Salts of active ingredients with polymeric counterions

US10610487B2 · kind B2 · utility

0Cited by

6References

17Claims

0Family size

Assignee

BASF SE

Inventors

Heiko Alexander Schiffter · Overath, DE
Maximilian Angel · Mutterstadt, DE
Karl Kolter · Ludwigshafen am Rhein, DE
Felicitas Guth · Neustadt, DE

Key dates

Filing date	Aug 17, 2016
Grant date	Apr 7, 2020
Priority date	—
Expiry date	Dec 8, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC08L2203/02
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Water-soluble polymeric salts of medicaments sparingly soluble in water consisting of a cationogenic medicament which, in uncharged form or as hydrochloride, has a solubility of less than 0.1% (m/m) in water, artificial intestinal juice or gastric juice, and an anionogenic water-soluble polymer having a solubility in water of at least 5% (m/m) in the pH range of 1 to 13 and which is obtained by free-radically initiated polymerization of a monomer mixture of i) 70 to 90% by weight N-vinylpyrrolidone and ii) 10 to 30% by weight acrylic acid, wherein the sum total of i) and ii) corresponds to 100% by weight.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.