Precision glycoconjugates as therapeutic tools
US10610576B2 · kind B2 · utility
1Cited by
5References
20Claims
0Family size
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Key dates
| Filing date | Mar 22, 2019 |
| Grant date | Apr 7, 2020 |
| Priority date | — |
| Expiry date | Mar 22, 2039 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/627
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present description relates to glycoconjugates, glycoconjugate immunogens and glycoconjugate vaccines comprising carbohydrate antigens coupled to immunogenic carrier proteins, or materials used for detection and screening of resulting antibodies. Improved methods of more directly and precisely conjugating carbohydrate antigens to free thiol groups of immunogenic carrier proteins are described, including “click-chemistry” approaches based on photocatalytic thiol-ene reactions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.