Functionalized 1,2,4,5-tetrazine compounds for use in bioorthogonal coupling reactions
US10611738B2 · kind B2 · utility
2Cited by
9References
14Claims
0Family size
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Key dates
| Filing date | Feb 26, 2018 |
| Grant date | Apr 7, 2020 |
| Priority date | — |
| Expiry date | Feb 26, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present application relates to functionalized 1,2,4,5-tetrazine compounds. The compounds are useful in compositions and methods using bioorthogonal inverse electron demand Diels-Alder cycloaddition reactions for the rapid and specific covalent delivery of a “payload” to a ligand bound to a biological target.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.