Patent · US Active

Salt form of DPPIV inhibitor and preparation method thereof

US10611774B2 · kind B2 · utility

0Cited by

1References

18Claims

0Family size

Assignee

SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES · CN

Inventors

Hong Liu · Shanghai, CN
Jiang Wang · Shanghai, CN
Jian Li · Shanghai, CN
Jia-He Li · Cockeysville, US
Jingya Li · Gothenburg, SE
Hualiang Jiang · Shanghai, CN
Xiaomin Luo · Shanghai, CN
Kaixian Chen · Shanghai, CN

Key dates

Filing date	Mar 22, 2017
Grant date	Apr 7, 2020
Priority date	—
Expiry date	Mar 22, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/13
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a salt form of (R)-methyl-2-(3-aminopiperidin-1-yl)-3-(2-cyanobenzyl)-4-carbonyl-3,4-dihydrothiophene[3,2-d]pyrimidine-6-carboxylic acid and a preparation method for the salt form. Also disclosed is a pharmaceutical composition of the formula I compound salt form. The salt form of the invention provides powerful in vivo hypoglycemic activity and is expected to be a novel pharmaceutical active ingredient for treating or preventing diabetes mellitus type 2 and/or complications of diabetes mellitus type 2

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.