Patent · US Active

Probes for improved melt discrimination and multiplexing in nucleic acid assays

US10612074B2 · kind B2 · utility

1Cited by

9References

19Claims

0Family size

Assignee

LUMINEX CORPORATION · US

Inventors

Doug WHITMAN · Round Rock, US
Nicolas Arab · Austin, US
Chuck Collins · Austin, US

Key dates

Filing date	Apr 28, 2017
Grant date	Apr 7, 2020
Priority date	—
Expiry date	Mar 16, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/6818
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Methods and compositions for the detection and quantification of nucleic acids are provided. In certain embodiments, methods involve the use of primers or probes that comprise a non-natural nucleotide linked to a reporter. Target nucleic acids are detected by the polymerization of a complementary probe or primer that incorporated a cognate non-natural nucleotide linked to a quencher.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.