Patent · US Active

Method for selecting a target nucleic acid sequence

US10612093B2 · kind B2 · utility

0Cited by

6References

37Claims

0Family size

Assignee

NAVINCI DIAGNOSTICS AB · SE

Inventors

Ulf Landegren · Uppsala, SE
Rachel Yuan Nong · Uppsala, SE

Key dates

Filing date	Jul 31, 2015
Grant date	Apr 7, 2020
Priority date	—
Expiry date	Jul 31, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/6827
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to a method of selecting a target region of interest (ROI) in a target nucleic acid molecule using a nucleic acid probe comprising sequences capable of directing the cleavage of a target nucleic acid molecule to release a fragment comprising the ROI and sequences capable of templating the circularisation and ligation of the target fragment. The circularised molecule thus obtained contains the selected ROI and may be subjected to further analysis and/or amplification etc. Also provided are probes and kits for use in such methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.