Patent · US Active

Competitive immunoassay test system for detecting a pyrogen

US10613105B2 · kind B2 · utility

0Cited by

2References

20Claims

0Family size

Assignee

Max-Planck-Gesellschaft zur Föderung der Wissenschaften e.V. · US

Inventors

Anke BURGER-KENTISCHER · Stuttgart, DE
Steffen Rupp · Stuttgart, DE

Key dates

Filing date	Nov 16, 2015
Grant date	Apr 7, 2020
Priority date	—
Expiry date	May 5, 2038

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/709
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention relates to a competitive immunoassay test system as well as a method to simply and rapidly detect pyrogens contained in a sample by means of the pyrogen binding domain of pattern recognition receptors. The test system comprises an assay carrier having at least one immobilized pyrogen binding domain of a pattern recognition receptor with a labeled, displaceable ligand, wherein the displacement of the ligand is indicated by a pyrogen contained in the sample by a color reaction of the labeling. The assay carrier preferably also has at least one immobilized ligand capture protein, which binds the displaced ligand and thereby initiates a color reaction of the labeling.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.