Patent · US Active

5-aromatic alkynyl substituted benzamide compound and preparation method, pharmaceutical composition, and use thereof

US10618900B2 · kind B2 · utility

1Cited by

2References

17Claims

0Family size

Assignee

SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES · CN

Inventors

Hong Liu · Shanghai, CN
Yu Zhou · Shanghai, CN
Dong ZHANG · Beijing, CN
Jian Li · Shanghai, CN
Hualiang Jiang · Shanghai, CN
Kaixian Chen · Shanghai, CN

Key dates

Filing date	Apr 15, 2016
Grant date	Apr 14, 2020
Priority date	—
Expiry date	Apr 15, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D491/10
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Compounds of formula I are provided. Also provided are methods of preparing the compounds of formula (I), and methods of using the compounds of formula (I) as a negative allosteric modulator of a metabotropic glutamate receptor (mGluR) subtype 5.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.