1-O-acetylbritannilatone spiro aryl isoxazoline compounds

US10618911B2 · kind B2 · utility

Assignee

• SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY · CN

Inventors

• Han Li · Xi'an, CN
• Yuzhi Liu · Xi'an, CN
• Nan Qin · Tianjin, CN
• Juan Xia · Xi'an, CN
• Shaomeng Pei · Xi'an, CN
• Chengyuan Liang · Xi'an, CN
• Lei Tian · Batou, CN

Key dates

• Filing date: Oct 23, 2018
• Grant date: Apr 14, 2020
• Expiry date: Oct 23, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D495/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A compound of chemical formula I: or formula II: or a pharmaceutical acceptable salt thereof is disclosed. R1 is OH or OAc; X is C or N; and R2 is H, alkyl, alkoxy, benzyloxy, haloalkyl, OH, CN, NO2, or halogen, provided that when X is N, R2 is nil.