SIRP-α agonist antibody
US10618976B2 · kind B2 · utility
5Cited by
1References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 8, 2016 |
| Grant date | Apr 14, 2020 |
| Priority date | — |
| Expiry date | Jan 27, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/75
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Compositions and methods are provided relating to anti-SIRPα agonist antibodies. The antibodies of the invention bind to human SIRPα, and activate signaling, thereby inhibiting processes mediated by SIRPα, including without limitation phagocytosis. Embodiments of the invention include isolated antibodies and derivatives and fragments thereof, pharmaceutical formulations comprising one or more of the anti-SIRPα agonist antibodies; and cell lines that produce these antibodies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.