Multispecific antibodies
US10618979B2 · kind B2 · utility
7Cited by
31References
11Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 1, 2016 |
| Grant date | Apr 14, 2020 |
| Priority date | — |
| Expiry date | Dec 1, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to heterodimerically-tethered bispecific protein complexes (according to the general formula of (A-X)2:(Y-B)2) and libraries/multiplexes thereof for use in research and therapy and in particular an in vitro/ex vivo method of detecting synergistic biological function of otherwise unknown pairs of targets. Such complexes may be used to capture soluble molecules secreted from a particular cell, in therapy, in research and for experimental purposes such as in assays to characterise patient populations by identifying cell populations relevant to a pathology or prognosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.