Increased ethanol production by thermophilic microorganisms with deletion of individual hfs hydrogenase subunits
US10619172B2 · kind B2 · utility
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Key dates
| Filing date | Jul 21, 2017 |
| Grant date | Apr 14, 2020 |
| Priority date | — |
| Expiry date | Nov 22, 2037 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02E50/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed are methods for engineering bacteria, for example, Thermoanaerobacterium saccharolyticum, that convert biomass to ethanol at high yield by deleting a single gene. Deletion of subunit A or subunit B of the hfs hydrogenase, but not deletion of subunit C or subunit D, results in an increase in ethanol yield.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.