Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing

US10619180B2 · kind B2 · utility

Assignee

• Accelerate Diagnostics, Inc. · US

Inventors

• Austin Ashby · Tucson, US
• Wayne Showalter · Tucson, US
• Jasmin Cote · Keyano, CA

Key dates

• Filing date: Mar 8, 2019
• Grant date: Apr 14, 2020
• Expiry date: Mar 8, 2039

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2035/1032
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A system for automated microorganism identification and antibiotic susceptibility testing comprising a reagent cartridge, a reagent stage, a cassette, a cassette, stage, a pipettor assembly, an optical detection system, and a controller is disclosed. The system is designed to dynamically adjust motor idle torque to control heat load and employs a fast focus process for determining the true focus position of an individual microorganism. The system also may quantify the relative abundance of viable microorganisms in a sample using dynamic dilution, and facilitate growth of microorganisms in customized media for rapid, accurate antimicrobial susceptibility testing.