Method and apparatus for performing liquid chromatography purification
US10620172B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 16, 2015 |
| Grant date | Apr 14, 2020 |
| Priority date | — |
| Expiry date | Sep 15, 2036 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D15/24
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The present invention relates to a method for performing liquid chromatography purification of one or more target molecules from a sample comprising: providing an eluent flow having one or more target molecules, measuring an output parameter indicative of the content of the one or more target molecules in the eluent flow, storing output parameter data, and dividing the eluent flow into consecutive eluent fractions, dividing the output parameter data into corresponding data fractions, in each data fraction obtaining a value indicative of characteristic behavior of the measured output parameter, identifying trends in the measured output parameter based upon the obtained value in consecutive data fractions, and identifying peak(s) in the measured output parameter correlated to eluent fractions based upon the identified trends, whereby information of identified peak(s) and correlated eluent fraction(s) can be presented and purified sample(s) from the eluent may be collected.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.