Antibody-mediated neutralization of Ebola viruses
US10620204B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 25, 2016 |
| Grant date | Apr 14, 2020 |
| Priority date | — |
| Expiry date | May 14, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure is directed to antibodies binding to and neutralizing ebolavirus and methods for use thereof. The present disclosure is directed to a method of detecting an ebolavirus infection in a subject comprising (a) contacting a sample from said subject with an antibody or antibody fragment having clone-paired heavy and light chain CDR sequences from Table 2, or an antibody fragment thereof; and (b) detecting ebolavirus glycoprotein in said sample by binding of said antibody or antibody fragment to antigen in said sample. In still further embodiments, the present disclosure concerns immunodetection kits for use with the immunodetection methods described above.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.