Use of nanoexpression to interrogate antibody repertoires
US10620219B2 · kind B2 · utility
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Key dates
| Filing date | Dec 13, 2017 |
| Grant date | Apr 14, 2020 |
| Priority date | — |
| Expiry date | Apr 5, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B30/04
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed herein are methods and compositions for using nanoexpression to interrogate antigen specificity within antibody repertoires. Also disclosed herein is an antibody display system composition comprising one or more recombinant nucleic acid sequences comprising a first nucleic acid sequence encoding a heavy chain variable region sequence or fragment thereof operatively linked to a first identification region sequence and a second nucleic acid sequence encoding a light chain variable region sequence or fragment thereof operatively linked to a second identification region sequence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.