Method and apparatus for rapid and selective tissue ablation with cooling
US10624693B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 17, 2016 |
| Grant date | Apr 21, 2020 |
| Priority date | — |
| Expiry date | Sep 17, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2090/061
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Systems, tools and methods are disclosed for the selective and rapid application of DC voltage to drive irreversible electroporation, with the system controller capable of being configured to apply voltages to independently selected subsets of electrodes and capable of generating at least one control signal to maintain the temperature near an electrode head within a desired range of values. Electrode clamp devices are also disclosed for generating electric fields to drive irreversible electroporation while modulating temperature to elevate the irreversible electroporation threshold utilizing a variety of means such as cooling fluid or solid state thermoelectric heat pumps.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.