SFRP5-derived peptide fragment and cosmetic composition for skin whitening containing same
US10626157B2 · kind B2 · utility
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Key dates
| Filing date | Jul 31, 2017 |
| Grant date | Apr 21, 2020 |
| Priority date | — |
| Expiry date | Jul 31, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/782
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided is a peptide fragment derived from secreted frizzled protein 5 (Sfrp5), i.e., a peptide fragment selected from the group consisting of the peptides as set forth in SEQ ID NOs: 1 to 9 and a cosmetic composition for skin-whitening and/or inhibiting skin pigmentation comprising the same as an active ingredient. The peptide fragment inhibits melanin formation in melanocytes, thereby having an inhibitory activity against skin pigmentation. Further provided is a reagent for researching or analyzing the inhibition of Wnt signaling pathways comprising the peptide fragment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.