Production of viruses in cell culture
US10626379B2 · kind B2 · utility
1Cited by
2References
20Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jan 25, 2019 |
| Grant date | Apr 21, 2020 |
| Priority date | — |
| Expiry date | Jan 25, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/18251
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to methods of replicating viruses in vitro. In particular, the invention relates to a genetically modified population of cells, and/or a population of cells treated with an exogenous compound, wherein the cells are capable of producing more virus than cells lacking the genetic modification and/or lacking treatment with the exogenous compound. The invention also relates to methods of producing populations of such cells, as well as the use of the viruses obtained to prepare vaccine compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.