Portable nucleic acid analysis system and high-performance microfluidic electroactive polymer actuators
US10626453B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Apr 14, 2015 |
| Grant date | Apr 21, 2020 |
| Priority date | — |
| Expiry date | Jul 13, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B60/12
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Devices, systems and methods for the parallel detection of a set of distinct nucleic acid sequences use multiple sequence amplification and simultaneous hybridization readout. An automated nucleic acid analysis system comprises in microfluidic connection sample lysis, purification, PCR and detection modules configured to detect in parallel distinct nucleic acid sequences via multiple sequence amplification and simultaneous microarray hybridization readout. High performance microfluidic electroactive polymer (μEAP) actuators comprising a dead-end fluid chamber in which a surface of the chamber is an electrode covered with an EAP layer of dielectric elastomer are configured for particle sorting.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.