Arrays of optical devices comprising integrated bandpass filters and methods of production

US10626457B2 · kind B2 · utility

Assignee

• PACIFIC BIOSCIENCES OF CALIFORNIA, INC. · US

Inventors

• Ravi Saxena · San Jose, US
• Annette Grot · Cupertino, US
• Nicolaas Tack · Buggenhout, BE
• Pilar Gonzalez · Leuven, BE
• Bert Du Bois · Blanden, BE
• Simone Severi · Leuven, BE

Key dates

• Filing date: Oct 28, 2016
• Grant date: Apr 21, 2020
• Expiry date: Aug 27, 2037

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2021/6471
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Arrays of integrated optical devices and their methods for production are provided. The devices include an integrated bandpass filter layer that comprises at least two multi-cavity filter elements with different central bandpass wavelengths. The device arrays are useful in the analysis of highly multiplexed optical reactions in large numbers at high densities, including biochemical reactions, such as nucleic acid sequencing reactions. The devices provide for the efficient and reliable coupling of optical excitation energy from an optical source to the optical reactions. Optical signals emitted from the reactions can thus be measured with high sensitivity and discrimination. The device arrays are well suited for miniaturization and high throughput.