Fluorescent marker for tissue staining containing phosphor-containing nanoparticle and method using same
US10627325B2 · kind B2 · utility
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18Claims
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Key dates
| Filing date | Feb 19, 2015 |
| Grant date | Apr 21, 2020 |
| Priority date | — |
| Expiry date | Feb 19, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/91205
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A tissue staining method which comprises: staining a tissue with a staining reagent wherein a biosubstance recognition site is bonded to particles carrying multiple fluorescent substances accumulated therein; in the stained tissue, counting fluorescent points or measuring fluorescent brightness; and evaluating the expression level of a biosubstance, which matches the biosubstance recognition site, in the aforesaid tissue on the basis of the number of the fluorescent points or fluorescent brightness that was measured.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.