Systems and methods for determining cross-linking distribution in a cornea and/or structural characteristics of a cornea
US10631726B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 11, 2018 |
| Grant date | Apr 28, 2020 |
| Priority date | — |
| Expiry date | Jan 11, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2005/0661
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
In a corneal measurement system, an optical element focuses an excitation light to an area of corneal tissue at a selected depth. In response, a fluorescing agent applied to the cornea generates a fluorescence emission. An aperture of a pinhole structure selectively transmits the fluorescence emission from the area of corneal tissue at the selected depth. A detector captures the selected fluorescence emission transmitted by the aperture and communicates information relating to a measurement of the selected fluorescence emission captured by the detector. A controller receives the information from the detector and determines a measurement of the fluorescing agent in the area of corneal tissue at the selected depth. The system may include a scan mechanism that causes the optical element to scan the cornea at a plurality of depths, and the controller may determine a measurement of the fluorescing agent in the cornea as a function of depth.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.