3D printed trans-modular scaffolds for grafting applications in segmental bone defects

US10631987B2 · kind B2 · utility

Assignee

• The Trustees of the Stevens Institute of Technology · US

Inventors

• Rebecca Chung · Hoboken, US
• Antonio Valdevit · Fishkill, US
• Dilhan M. Kalyon · Teaneck, US

Key dates

• Filing date: Jul 25, 2017
• Grant date: Apr 28, 2020
• Expiry date: Jul 25, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2533/40
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A bone repair scaffold having two moduli that match those of the cancellous and cortical bone in a patient receiving a bone graft/implant. The bone repair scaffold possesses increased mechanical properties to sustain physiological loading and biologically active capability to facilitate bone fusion. The bone repair scaffold may be 3D-printed, which allows for a variety of scaffold designs and configurations. Pore size, interconnected porosity, shape, and modulus of the bone repair scaffold may be modified for different bone graft applications, whether it is used as filler for bone cancer resections or trauma, or as a fusion device in cases of surgery. Depending on the defect location of the bone shaft, the relative porosity of the scaffold may be modified to account for changes in cortical bone thickness. A method for treating a bone defect using the bone repair scaffold is also disclosed.