Patent · US Active

Application of obacunone in preparation of drug for preventing and treating lung damage and pulmonary fibrosis

US10632100B2 · kind B2 · utility

0Cited by

0References

10Claims

0Family size

Assignee

GUANGDONG PROVINCIAL HOSPITAL OF TRADITIONAL CHINESE MEDICINE · CN

Inventors

Yang Xu · Wenhe, CN
Shengmei Xu · 流花街道, CN
Weimin Chen · Linhu, CN

Key dates

Filing date	Feb 28, 2017
Grant date	Apr 28, 2020
Priority date	—
Expiry date	Feb 28, 2037

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P11/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed is application of obacunone in the manufacture of a medicament for prevention or treatment of lung injury and pulmonary fibrosis. The medicament consists of obacunone and pharmaceutically acceptable auxiliaries and additives, wherein obacunone is 3% to 25% by mass in the medicament. The obacunone in the medicament can inhibit bleomycin-induced lung injury and pulmonary fibrosis in mice, and regulate the expression of the inflammation-associated cytokines in the bleomycin-induced injured lung tissue in mice.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.