Sample processing devices, and methods of use thereof

US10632469B2 · kind B2 · utility

Assignee

• DOUGLAS SCIENTIFIC, LLC · US

Inventors

• Robert Hjelseth · Loretto, US
• Cory Hodgson · Alexandria, US
• Andrew Bristow · Alexandria, US
• Mark Baumgartner · Alexandria, US
• David Sellnow · Alexandria, US
• Cassie Keppel · Saint Louis, US
• John Steckelberg · Sauk Centre, US
• Paul Newman · Thornley with Wheatley, GB

Key dates

• Filing date: Dec 13, 2018
• Grant date: Apr 28, 2020
• Expiry date: Dec 13, 2038

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01L2400/0457
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

Embodiments of the invention provide a filter kit including filters for processing a biological sample. Some embodiments include a filter cap in a tube kit with a first tube containing a buffer solution and a second tube containing a lyophilized master mix. Some embodiments include a method of processing a sample using the kit including mixing a biological sample in a first tube with the buffer solution, positioning the filter cap in the first tube, positioning a second tube on the filter cap, flipping the first tube, the filter cap, and the second cap to filter the biological sample and buffer solution mixture with the filter cap as it flows from the first tube to the second tube. Some embodiments include structure enabling transfer of materials through inline flow between the tubes. Some further embodiments include integrated structure for sample pulverization with integrated buffer and lyophilized master mix.