Substituted tricyclic heterocyclic compounds
US10633354B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Aug 31, 2017 |
| Grant date | Apr 28, 2020 |
| Priority date | — |
| Expiry date | Aug 31, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/655354
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are compounds of Formula (I), Formula (II), Formula (III), and Formula (IV) or salts thereof, wherein R2 is —OH or —OP(O)(OH)2; and R1 is defined herein. Also disclosed are methods of using such compounds as selective agonists for G protein coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.