Methods and apparatus for perfusion and environment control of microplate labware

US10633624B2 · kind B2 · utility

Assignees

• Essen Instruments, Inc. · US
• National Research Council of Canada · CA

Inventors

• Kirk Schroeder · Ann Arbor, US
• Bradley D. Neagle · Ann Arbor, US
• Eric Endsley · Saline, US
• Daniel Appledorn · Ann Arbor, US
• Keith Morton · Saint-Bruno-de-Montarville, CA

Key dates

• Filing date: Jul 1, 2019
• Grant date: Apr 28, 2020
• Expiry date: Jul 1, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12M41/46
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Systems, methods, and apparatuses of controlling fluid flow are disclosed. An apparatus includes a first microplate having a first open portion and defining one or more first wells therein, a second microplate having a second open portion and defining one or more second wells therein, and a pneumatic lid constructed of styrene ethylene butylene styrene (SEBS). The pneumatic lid extends over the first open portion and the second open portion and includes one or more microfluidic channels that fluidly couple the one or more first wells to the one or more second wells. The pneumatic lid provides an airtight seal over the first microplate and the second microplate.