Patent · US Active

Proteinases with improved properties

US10633644B1 · kind B1 · utility

4Cited by
3References
24Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 18, 2019
Grant dateApr 28, 2020
Priority date
Expiry dateDec 18, 2039

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Y304/21064
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Provided herein is a thermolabile proteinase and methods of using the same. In some embodiments, the thermolabile proteinase may comprise an amino acid sequence that is at least 90% identical to any of SEQ ID NOs:1-11 and at least one amino acid substitution in helix 3. The thermolabile proteinase is active at a temperature in the range of 4° C.-40° C. and is inactivated by raising the temperature to above 50° C., where the proteinase is substantially inactive at 65° C.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.