Bio-adaptable implantable sensor apparatus and methods
US10638962B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 29, 2016 |
| Grant date | May 5, 2020 |
| Priority date | — |
| Expiry date | Jun 27, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2562/247
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Biocompatible implantable sensor apparatus and methods of implantation and use. In one embodiment, the sensor apparatus is an oxygen-based glucose sensor having biocompatibility features that mitigate the host tissue response. In one variant, these features include use of a non-enzymatic membrane over each of the individual analyte detectors so as to preclude contact of the surrounding tissue with the underlying enzyme or other matrix, and mitigate vascularization, and insulation of the various electrodes and associated electrolytic processes of the sensor from the surrounding tissue. In one implementation, the sensor region of the implanted apparatus is configured to interlock or imprint the surrounding tissue so as to promote a high degree of glucose molecule diffusion into the individual detectors, and a constant and predictable sensor to blood vessel interface, yet preclude the tissue from bonding to the sensor, especially over extended periods of implant.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.