Podophyllotoxin derivative with 4-position nitrogen substitution and preparation method and application thereof
US10639295B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Aug 2, 2016 |
| Grant date | May 5, 2020 |
| Priority date | — |
| Expiry date | Aug 2, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/573
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound represented by formula (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable formulation prepared using the compound and the salt. The compound represented by formula (I) or the pharmaceutically acceptable salt exhibits significantly higher buildup and concentration in the lungs compared to other tissues, a longer dwell time in the lungs, and/or elevated pharmaceutical efficacy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.