Compounds
US10640498B2 · kind B2 · utility
4Cited by
0References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 16, 2017 |
| Grant date | May 5, 2020 |
| Priority date | — |
| Expiry date | Feb 16, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to novel compounds of formula (I) and methods for the manufacture of inhibitors of deubiquitylating enzymes (DUBs). In particular, the invention relates to the inhibition of ubiquitin C-terminal hydrolase 30 or ubiquitin specific peptidase 30 (USP30). The invention further relates to the use of DUB inhibitors in the treatment of conditions involving mitochondrial dysfunction and in the treatment of cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.