Difluoromethyl-aminopyridines and difluoromethyl-aminopyrimidines
US10640516B2 · kind B2 · utility
3Cited by
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21Claims
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Key dates
| Filing date | Nov 10, 2015 |
| Grant date | May 5, 2020 |
| Priority date | — |
| Expiry date | Nov 10, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D519/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to novel phosphoinositide 3-kinase (PI3k), mammalian target of rapamycin (mTOR) and PI3k-related kinase (PIKKs) inhibitor compounds of formula (I), wherein X1, X2 and X3 are N or CH, with the proviso that at least two of X1, X2 and X3 are N; Y is N or CH, These compounds are useful, either alone or in combination with further therapeutic agents, for treating disorders mediated by lipid kinases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.