Polypeptides for inhibiting complement activation
US10640540B2 · kind B2 · utility
1Cited by
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10Claims
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Key dates
| Filing date | Dec 23, 2016 |
| Grant date | May 5, 2020 |
| Priority date | — |
| Expiry date | Dec 23, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/74
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a polypeptide comprising a C3 convertase effector domain, a C5 convertase effector domain and optionally a terminal complex inhibitory effector domain which is resistant to deregulation by physiologic FHR-Proteins and has a dimerization motif, and to its therapeutic use.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.