Method of enhancing absorption spectral signals of biological samples in terahertz wavebands

US10641703B2 · kind B2 · utility

Assignee

• University of Shanghai for Science and Technology · CN

Inventors

• Yan Peng · Shanghai, CN
• Tengfei Zhang · Zhenjiang, CN
• Yiming Zhu · Hefei, CN
• Bowei Xu · Shanghai, CN
• Wanqing Chen · Shanghai, CN
• Binbin Qi · Shanghai, CN
• Xiuping Zhang · Dongguan, CN

Key dates

• Filing date: Jun 30, 2018
• Grant date: May 5, 2020
• Expiry date: Sep 9, 2038

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2001/368
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Disclosed is a method of enhancing absorption spectral signals of a biological sample in a terahertz waveband in which the biological sample are embedded and supported with black silicon. In the method, the biological sample are filled between the surface micro-nano structures of a black silicon material and then freeze-dried. When the terahertz wave is incident upon the black silicon material, multiple reflections will occur between the micro-nano structures, so that the terahertz wave passes through the biological sample multiple times to increase the distance of interaction between the terahertz waves and the biological sample, allowing for enhanced absorption spectral signals of the biological sample and improved identifiability of the biological sample. The method is simple and easy to implement and low in cost.