Selective high-affinity polydentate ligands and methods of making such
US10646502B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Sep 13, 2017 |
| Grant date | May 12, 2020 |
| Priority date | — |
| Expiry date | Sep 13, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.