Apoptotic bodies

US10646518B2 · kind B2 · utility

Assignees

• ALFRED E. MANN INSTITUTE FOR BIOMEDICAL ENGINEERING AT THE UNIVERSITY OF SOUTHERN CALIFORNIA · US
• University of Southern California · US

Inventors

• Songtao Shi · Los Angeles, US
• Dawei Liu · Suzhou, CN
• Cunye Qu · Alhambra, US

Key dates

• Filing date: Aug 7, 2015
• Grant date: May 12, 2020
• Expiry date: Sep 21, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N5/0663
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This disclosure relates to apoptotic bodies. The disclosure particularly relates to a composition comprising the apoptotic bodies. The disclosure further relates to preparation of apoptotic bodies from stem cells. The disclosure also relates to medical treatments comprising the use of the composition comprising the apoptotic bodies. The apoptotic bodies may comprise apoptotic stem cells. The apoptosis of a cell may be induced by a starvation method, an ultra-violet irradiation method, a thermal stress method, a staurosporine method, or a combination thereof.