Method for preparing water extract of ashwagandha leaves which has enhanced anti-cancer activity utilizing cyclodextrin, and pharmaceutical composition containing ashwagandha leaves
US10646532B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jan 29, 2015 |
| Grant date | May 12, 2020 |
| Priority date | — |
| Expiry date | Jan 17, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2236/53
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
It is an object of the present invention to provide a method for preparing a water extract of ashwagandha, which comprises increasing the amounts of withanone and withaferin A contained as active ingredients in the water extract of ashwagandha leaves. In addition, it is another object of the present invention to more economically and simply provide a pharmaceutical composition comprising ashwagandha leaves.The present invention relates to a method for preparing a water extract of ashwagandha leaves, which comprises extracting ashwagandha leaves with water in the presence of cyclodextrin, and a method for enhancing the anticancer activity of the water extract of ashwagandha leaves. The present invention also relates to a pharmaceutical composition for treating or preventing cancer, comprising the water extract of ashwagandha leaves. The present invention further relates to a pharmaceutical composition comprising dry powders of ashwagandha leaves and cyclodextrin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.