Patent · US Active

Substituted pyrimidines for preventing or treating cancer and inflammatory diseases

US10647686B2 · kind B2 · utility

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10Claims
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Assignee

Inventors

Key dates

Filing dateNov 1, 2017
Grant dateMay 12, 2020
Priority date
Expiry dateNov 1, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D405/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to compounds represented by Formula 1 These compounds according to the present invention remarkably inhibits activity of DRAK that inhibits signal systems of TGF-β, which is known to suppress cancer growth, and thus the novel pyrimidine compounds can be used as a pharmaceutical composition for preventing or treating cancer and can be used as a pharmaceutical composition for preventing or treating inflammatory disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.