Compounds and use thereof in the expansion of hematopoietic stem cells and/or hematopoietic progenitor cells
US10647718B2 · kind B2 · utility
2Cited by
2References
18Claims
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Key dates
| Filing date | Apr 21, 2015 |
| Grant date | May 12, 2020 |
| Priority date | — |
| Expiry date | Oct 20, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of general formula or salts or prodrugs thereof, are provided and described herein. The compounds are useful to expand hematopoietic stem cell and/or hematopoietic progenitor cell populations. Particularly, the hematopoietic cells are human cells. The compounds are also useful in the medical treatment of hematopoietic disorder/malignancy, an autoimmune disease and/or an inherited immune-deficient disease in a subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.